Landau (1911) proved that for any fixed ,
as , where the sum runs over the nontrivial Riemann zeta function zeros and is the Mangoldt function. Here, "fixed " means that the constant implicit in depends on and, in particular, as approaches a prime or a prime power, the constant becomes large.
Landau's formula is roughly the derivative of the explicit formula.
Landau's formula is quite extraordinary. If is not a prime or a prime power, then and the sum grows as a constant times . But if is a prime or a prime power, then and the sum grows much faster, like a constant times . This exhibits an amazing connection between the primes and the s; somehow the zeros "recognize" when is a prime and cause large contributions to the sum.