Two closed simply connected 4-manifolds are homeomorphic iff they have the same bilinear form and the same Kirby-Siebenmann
invariant
.
Any
can be realized by such a manifold. If
is odd for some
, then either value of
can be realized also. However, if
is always even, then
is determined by
, being congruent to 1/8 of the signature of
. Here,
is a symmetric bilinear form with
determinant
(Milnor).
In particular, if
is a homotopy sphere, then
and
, so
is homeomorphic to
.